Mark K. Saville

p53 isoforms can regulate p53 transcriptional activity

Jean‐Christophe Bourdon, Kenneth Fernandes, F Murray-Zmijewski et al. · Genes & Development · 2005 · 792 citations · Full text

Mdm2-Mediated NEDD8 Conjugation of p53 Inhibits Its Transcriptional Activity

Dimitris P. Xirodimas, Mark K. Saville, Jean‐Christophe Bourdon et al. · Cell · 2004 · 556 citations · Full text

Medicine, Mdm2-mediated Nedd8 Conjugation, Tumor Suppressor +4

The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2

Lauren Stevenson, Alison Sparks, Nerea Allende-Vega et al. · The EMBO Journal · 2007 · 276 citations · Full text

Molecular Biology, Tumor Suppressor, P53 Pathway +4

Lysine‐63‐linked ubiquitination is required for endolysosomal degradation of class I molecules

Lidia M. Duncan, Siân C. Piper, Roger B. Dodd et al. · The EMBO Journal · 2006 · 271 citations · Full text

An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo

Carol Midgley, Joana Desterro, Mark K. Saville et al. · Oncogene · 2000 · 250 citations

Mdm2-dependent Ubiquitination, N-terminal P14arf Peptide, Medicine +6