Fast and efficient generation of knock-in human organoids using homology-independent CRISPR–Cas9 precision genome editing

Benedetta Artegiani, Delilah Hendriks, Joep Beumer, +7

Nature Cell Biology

Efficient GenerationEngineeringGeneticsGenetic EngineeringSynthetic Biology +9

Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25

Yaoyun Kuang, Xuan Zheng, Lin Zhang, +6

Journal of Extracellular Vesicles

Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation

Gui-Wei He, Lin Lin, Jeff DeMartino, +16

Cell stem cell

OrganoidTracker: Efficient cell tracking using machine learning and manual error correction

Rutger N.U. Kok, Laetitia Hebert, Guizela Huelsz‐Prince, +6

PLoS ONE

Cell TrajectoriesEngineeringMachine LearningDigital PathologyTrajectory Analysis +23

Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice

Xuan Zheng, Lin Zhang, Yi Kuang, +12

Translational Stroke Research

Direct imaging of the circular chromosome in a live bacterium

Fabai Wu, Aleksandre Japaridze, Xuan Zheng, +3

Nature Communications

Cell Boundary Confinement Sets the Size and Position of the E. coli Chromosome

Fabai Wu, Pinaki Swain, Louis Kuijpers, +9

Current Biology

ChromatinE. Coli ChromosomeProkaryotic SystemNatural SciencesMolecular Biology +8

DNA surface exploration and operator bypassing during target search

Emil Marklund, Brad Van Oosten, Guanzhong Mao, +11

Nature

ChromatinNatural SciencesDna AnalysisDna ReplicationMolecular Biology +5

Very Delayed Remote Ischemic Post-conditioning Induces Sustained Neurological Recovery by Mechanisms Involving Enhanced Angioneurogenesis and Peripheral Immunosuppression Reversal

Thorsten R. Doeppner, Bozena Zechmeister, Britta Kaltwasser, +6

Frontiers in Cellular Neuroscience

Hind LimbsCerebrovascular DiseaseMotor ControlCerebral Vascular RegulationNeurovascular Disease +21

Neural Progenitor Cell-Derived Extracellular Vesicles Enhance Blood-Brain Barrier Integrity by NF-κB (Nuclear Factor-κB)-Dependent Regulation of ABCB1 (ATP-Binding Cassette Transporter B1) in Stroke Mice

Lin Zhang, Irina Graf, Yaoyun Kuang, +9

Arteriosclerosis Thrombosis and Vascular Biology