Pietro Grossi

An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics

Luisella Vignati, Elisa Turlizzi, Sonia Monaci et al. · Toxicology · 2005 · 91 citations

Metabolite Toxicity, Biochemistry, Medicine +10

An in vivo and in vitro comparison of CYP induction in rat liver and intestine using slices and quantitative RT-PCR

Marcella Martignoni, Ruben de Kanter, Pietro Grossi et al. · Chemico-Biological Interactions · 2004 · 66 citations

Hepatology, Quantitative Rt-pcr, Gastrointestinal Pharmacology +9

A human and mouse pregnane X receptor reporter gene assay in combination with cytotoxicity measurements as a tool to evaluate species-specific CYP3A induction

Luisella Vignati, Alessia Bogni, Pietro Grossi et al. · Toxicology · 2004 · 54 citations

Knockout Mouse, Molecular Pharmacology, Reporter Gene Assay +9

Phase I and phase II metabolic activities are retained in liver slices from mouse, rat, dog, monkey and human after cryopreservation

Marcella Martignoni, Mario Monshouwer, Ruben de Kanter et al. · Toxicology in Vitro · 2003 · 36 citations

Animal Physiology, Energy Metabolism, Biochemistry +13

An in vivo and in vitro comparison of CYP gene induction in mice using liver slices and quantitative RT-PCR

Marcella Martignoni, Ruben de Kanter, Pietro Grossi et al. · Toxicology in Vitro · 2005 · 26 citations

Hepatology, Liver Slices, Quantitative Rt-pcr +8