Luca Massimino

Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson’s Disease Models

Angelo Iannielli, Simone Bido, Lucrezia Folladori et al. · Cell Reports · 2018 · 225 citations · Full text

dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice

Gaia Colasante, Gabriele Lignani, Simone Brusco et al. · Molecular Therapy · 2019 · 215 citations · Full text

Dravet Syndrome Mice, Molecular Neuroscience, Experimental Neuropathology +7

Direct Conversion of Fibroblasts into Functional Astrocytes by Defined Transcription Factors

Massimiliano Caiazzo, Serena Giannelli, Pierluigi Valente et al. · Stem Cell Reports · 2014 · 213 citations · Full text

Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity

Simone Bido, Sharon Muggeo, Luca Massimino et al. · Nature Communications · 2021 · 175 citations · Full text

Rapid Conversion of Fibroblasts into Functional Forebrain GABAergic Interneurons by Direct Genetic Reprogramming

Gaia Colasante, Gabriele Lignani, Alicia Rubio et al. · Cell stem cell · 2015 · 163 citations

Neuroregeneration, Developmental Biology, Medicine +5