Simone Bido

Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson’s Disease Models

Angelo Iannielli, Simone Bido, Lucrezia Folladori et al. · Cell Reports · 2018 · 225 citations · Full text

dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice

Gaia Colasante, Gabriele Lignani, Simone Brusco et al. · Molecular Therapy · 2019 · 215 citations · Full text

Dravet Syndrome Mice, Molecular Neuroscience, Experimental Neuropathology +7

Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity

Simone Bido, Sharon Muggeo, Luca Massimino et al. · Nature Communications · 2021 · 175 citations · Full text

Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson’s disease

Simone Bido, Federico N. Soria, Rebecca Z. Fan et al. · Scientific Reports · 2017 · 151 citations · Full text

AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy

Giuseppe Morabito, Serena Giannelli, Gabriele Ordazzo et al. · Molecular Therapy · 2017 · 126 citations · Full text