Simone Brusco

dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice

Gaia Colasante, Gabriele Lignani, Simone Brusco et al. · Molecular Therapy · 2019 · 215 citations · Full text

Dravet Syndrome Mice, Molecular Neuroscience, Experimental Neuropathology +7

Frataxin gene editing rescues Friedreich’s ataxia pathology in dorsal root ganglia organoid-derived sensory neurons

Pietro Giuseppe Mazzara, Sharon Muggeo, Mirko Luoni et al. · Nature Communications · 2020 · 77 citations · Full text

Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome

Nicholas Valassina, Simone Brusco, Alessia Salamone et al. · Nature Communications · 2022 · 69 citations · Full text

Nocturnal frontal lobe epilepsy with paroxysmal arousals due to CHRNA2 loss of function

Valerio Conti, Patrizia Aracri, Laura Chiti et al. · Neurology · 2015 · 40 citations · Full text

Postnatal Changes in K+/Cl− Cotransporter-2 Expression in the Forebrain of Mice Bearing a Mutant Nicotinic Subunit Linked to Sleep-Related Epilepsy

Alida Amadeo, Aurora Coatti, Patrizia Aracri et al. · Neuroscience · 2018 · 16 citations · Full text

Molecular Neuroscience, Molecular Physiology, Developmental Biology +14