Concepedia

Wieslawa Maniara

WM

15

Publications

1.4K

Citations

14

H-Index

1989

Active since

Affiliations

Novartis (Switzerland)(Current)

Novartis (United States)

Johnson University

Novartis Institutes for BioMedical Research

Environmental and Occupational Health Sciences Institute

Wieslawa Maniara is an author at Novartis (Switzerland) specializing in pharmacology, medicine, and drug discovery.

Top concepts

MedicinePharmacologyDrug DiscoveryBiochemistryPharmacotherapyNatural SciencesMedicinal ChemistryDrug DevelopmentMolecular PharmacologyChemical Biology

Publications per year

1989–2015

15

Publications

15

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

Shifeng Pan, Xu Wu, Jiqing Jiang et al. · ACS Medicinal Chemistry Letters · 2010 · 325 citations · Full text

Selective Smoothened Antagonist, Chemoprevention Strategy, Novel Therapy +14

Effects of Aliskiren on Blood Pressure, Albuminuria, and (Pro)Renin Receptor Expression in Diabetic TG(mRen-2)27 Rats

David L. Feldman, Xuan Hong, Aurélie Contrepas et al. · Hypertension · 2008 · 285 citations · Full text

Hypertension, Renin Receptor Expression, Blood Pressure +17

1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor Activity

Karen Miller‐Moslin, Stefan Peukert, Rishi K. Jain et al. · Journal of Medicinal Chemistry · 2009 · 106 citations · Full text

Pharmaceutical Science, Antitumor Activity, Pharmacotherapy +16

Investigation of Functionally Liver Selective Glucokinase Activators for the Treatment of Type 2 Diabetes

Gregory R. Bebernitz, Valérie Beaulieu, Bethany A. Dale et al. · Journal of Medicinal Chemistry · 2009 · 91 citations

Gk Enzyme, Glycobiology, Pharmaceutical Chemistry +18

Discovery of NVP‐LEQ506, a Second‐Generation Inhibitor of Smoothened

Stefan Peukert, Feng He, Miao Dai et al. · ChemMedChem · 2013 · 88 citations

Molecular Pharmacology, Continued Optimization, Competitor Compound +15

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