Tadayoshi Karasawa

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance

Takashi Matsuzaka, Hitoshi Shimano, Naoya Yahagi et al. · Nature Medicine · 2007 · 553 citations

Life Sciences, Biochemistry, Endocrinology +16

Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure

Naoya Yamada, Tadayoshi Karasawa, Hiroaki Kimura et al. · Cell Death and Disease · 2020 · 341 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

Iron overload as a risk factor for hepatic ischemia-reperfusion injury in liver transplantation: Potential role of ferroptosis

Naoya Yamada, Tadayoshi Karasawa, Taiichi Wakiya et al. · American Journal of Transplantation · 2020 · 278 citations · Full text

Medicine, Biochemistry, Inflammation +14

Inflammasome Activation by Mitochondrial Oxidative Stress in Macrophages Leads to the Development of Angiotensin II–Induced Aortic Aneurysm

Fumitake Usui, Koumei Shirasuna, Hiroaki Kimura et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2014 · 191 citations · Full text

Veterinary Medicine, Cardiology, Pathobiology +17

Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice

Fumitake Usui, Koumei Shirasuna, Hiroaki Kimura et al. · Biochemical and Biophysical Research Communications · 2012 · 182 citations

Life Sciences, Immunology, Pathobiology +14