Ryan Brand

Somatic mutations and cell identity linked by Genotyping of Transcriptomes

Anna S. Nam, Kyu-Tae Kim, Ronan Chaligné et al. · Nature · 2019 · 320 citations

Developmental Biology, Somatic Mutations, Somatic Variant +10

Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia

Federico Gaiti, Ronan Chaligné, Hongcang Gu et al. · Nature · 2019 · 261 citations · Full text

Hematological Malignancy, Chromatin, Epigenetic Evolution +5

Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL

Alessandro Pastore, Federico Gaiti, Sydney X. Lu et al. · Nature Communications · 2019 · 84 citations · Full text

Histone Modifications, Epigenetic Change, Genetics +21

LM-GVP: an extensible sequence and structure informed deep learning framework for protein property prediction

Zichen Wang, Steven A. Combs, Ryan Brand et al. · Scientific Reports · 2022 · 83 citations · Full text

Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment

Adam J. Widman, Minita Shah, Amanda Frydendahl et al. · Nature Medicine · 2024 · 76 citations · Full text

Engineering, Cancer Detection, Medicine +11