Louise A. Griffiths

Statistics

Publications

Citations

190

H-Index

Active since

2016

Affiliations

AstraZeneca (United Kingdom)(Current)

Cancer Research UK Manchester Institute

University of Manchester

Louise A. Griffiths is an author at AstraZeneca (United Kingdom) specializing in dna damage signaling, poly(adp-ribose) glycohydrolase, and dna repair.

Publications per year

2016–2018

Publications

First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib

Dominic I. James, Kate M. Smith, Allan M. Jordan et al. · ACS Chemical Biology · 2016 · 148 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides

Bohdan Waszkowycz, Kate M. Smith, Alison E. McGonagle et al. · Journal of Medicinal Chemistry · 2018 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

An assay to measure poly(ADP ribose) glycohydrolase (PARG) activity in cells

Dominic I. James, Stephen T. Durant, Kay Eckersley et al. · F1000Research · 2016 · 10 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

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