Concepedia

Christopher S. Theile

CS

22

Publications

2K

Citations

19

H-Index

2011

Active since

Affiliations

Whitehead Institute for Biomedical Research(Current)

Massachusetts Institute of Technology

Alnylam Pharmaceuticals (United States)

Harvard University

Howard Hughes Medical Institute

Christopher S. Theile is an author at Whitehead Institute for Biomedical Research specializing in natural sciences, medicine, and molecular biology.

Top concepts

Natural SciencesMedicineBiochemistryMolecular BiologyDrug DiscoveryProtein EngineeringPharmacologyBiomolecular EngineeringProteomicsEngineering

Publications per year

2011–2023

22

Publications

22

Site-specific C-terminal and internal loop labeling of proteins using sortase-mediated reactions

Carla P. Guimarães, Martin D. Witte, Christopher S. Theile et al. · Nature Protocols · 2013 · 350 citations · Full text

Protein Assembly, Biochemistry, Protein Folding +12

Site-specific N-terminal labeling of proteins using sortase-mediated reactions

Christopher S. Theile, Martin D. Witte, Annet E. M. Blom et al. · Nature Protocols · 2013 · 274 citations · Full text

Natural Sciences, Molecular Biology, Molecular Sorting +5

Investigating the pharmacodynamic durability of GalNAc–siRNA conjugates

Christopher R. Brown, Swati Gupta, June Qin et al. · Nucleic Acids Research · 2020 · 265 citations · Full text

Sirna Accumulation, Molecular Pharmacology, Medicinal Chemistry +15

Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates

Kirk Brown, Jayaprakash K. Nair, Maja M. Janas et al. · Nature Biotechnology · 2022 · 225 citations · Full text

Rnai Therapeutics, Liver Physiology, Gene Delivery +5

5′‐(<i>E</i>)‐Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA–GalNAc Conjugates

Rubina Parmar, Jennifer L. S. Willoughby, Jingxuan Liu et al. · ChemBioChem · 2016 · 132 citations

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