J.K. Muckelbauer - Concepedia

Author

J.K. Muckelbauer

Bristol-Myers Squibb (United States)ORCID

Also Known As

J. K. Muckelbauer, J. Muckelbauer, J.K. Muckelbauer, Jodi K Muckelbauer, Jodi K. Muckelbauer, Jodi Muckelbauer, Muckelbauer, Jodi K.

Publications

1.6K

Citations

H-Index

Concepts

All Affiliations

Bristol-Myers Squibb (United States)Bristol-Myers Squibb (Germany)Bristol-Myers Squibb (India)Biocon (India)Purdue University West Lafayette

About

J.K. Muckelbauer is an author at Bristol-Myers Squibb (United States) specializing in medicine, drug discovery, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	16	19	886
2	Natural Sciences	14	16	470
3	Biochemistry	12	14	431
4	Engineering	3	3	62
5	Biomolecular Engineering	2	2	64

J.K. Muckelbauer

Publications

1.5K

Citations

H-Index

Page 1

	Year	Citations
The structure of coxsackievirus B3 at 3.5 å resolution J.K. Muckelbauer, Marcia J. Kremer, Iwona Minor, Structure Virus StructurePathogenesisCoxsackievirus B3VirologyVirus Classification	1995	279
Discovery of 6-Fluoro-5-(<i>R</i>)-(3-(<i>S</i>)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4<i>H</i>)-yl)-2-methylphenyl)-2-(<i>S</i>)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1<i>H</i>-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers Scott H. Watterson, George V. De Lucca, Qing Shi, Journal of Medicinal Chemistry	2016	142
Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain John S. Tokarski, Adriana Zupa-Fernandez, Jeffrey Tredup, Journal of Biological Chemistry	2015	112
Quinazolines as cyclin dependent kinase inhibitors Thais M. Sielecki, Tricia L. Johnson, Jie Liu, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryMedicineMechanism Of ActionPharmacotherapyPharmacology	2001	85
Identification of <i>N</i>-Methyl Nicotinamide and <i>N</i>-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2) Ryan Moslin, Yanlei Zhang, Stephen T. Wrobleski, Journal of Medicinal Chemistry	2019	84
Structure determination of coxsackievirus B3 to 3.5 Å resolution J.K. Muckelbauer, Monique Kremer, Iwona Minor, Acta Crystallographica Section D Biological Crystallography	1995	67
Small Molecule Reversible Inhibitors of Bruton’s Tyrosine Kinase (BTK): Structure–Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9<i>H</i>-carbazole-1-carboxamide (BMS-935177) George V. De Lucca, Qing Shi, Qingjie Liu, Journal of Medicinal Chemistry Tyrosine KinaseImmunologyPharmacotherapyChemical BiologyPharmaceutical Chemistry	2016	50
Identification of Imidazo[1,2-<i>b</i>]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors Chunjian Liu, James C. Lin, Ryan Moslin, ACS Medicinal Chemistry Letters	2019	49
Acyl Guanidine Inhibitors of β-Secretase (BACE-1): Optimization of a Micromolar Hit to a Nanomolar Lead via Iterative Solid- and Solution-Phase Library Synthesis Samuel W. Gerritz, Weixu Zhai, Shuhao Shi, Journal of Medicinal Chemistry Flap Residue Gln73Drug TargetAcyl Guanidine InhibitorsLead IdentificationChemical Biology	2012	48
Identification of imidazo[1,2-<i>b</i>]pyridazine TYK2 pseudokinase ligands as potent and selective allosteric inhibitors of TYK2 signalling Ryan Moslin, Daniel S. Gardner, Joseph B. Santella, MedChemComm	2016	48

Page 1