J.K. Muckelbauer

The structure of coxsackievirus B3 at 3.5 å resolution

J.K. Muckelbauer, Marcia J. Kremer, Iwona Minor et al. · Structure · 1995 · 280 citations

Life Sciences, Biology, Molecular Biology +12

Discovery of 6-Fluoro-5-(<i>R</i>)-(3-(<i>S</i>)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4<i>H</i>)-yl)-2-methylphenyl)-2-(<i>S</i>)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1<i>H</i>-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers

Scott H. Watterson, George V. De Lucca, Qing Shi et al. · Journal of Medicinal Chemistry · 2016 · 146 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain

John S. Tokarski, Adriana Zupa-Fernandez, Jeffrey Tredup et al. · Journal of Biological Chemistry · 2015 · 116 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Identification of <i>N</i>-Methyl Nicotinamide and <i>N</i>-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2)

Ryan Moslin, Yanlei Zhang, Stephen T. Wrobleski et al. · Journal of Medicinal Chemistry · 2019 · 92 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Quinazolines as cyclin dependent kinase inhibitors

Thais M. Sielecki, Tricia L. Johnson, Jie Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 86 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10