Jian Jiang

Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors

Noel D. D’Angelo, Tae‐Seong Kim, Kristin L. Andrews et al. · Journal of Medicinal Chemistry · 2011 · 118 citations · Full text

Drug Target, Pharmacotherapy, Benzothiazole Phosphoinositide 3-Kinase +21

Combretastatin A4 Nanodrug‐Induced MMP9 Amplification Boosts Tumor‐Selective Release of Doxorubicin Prodrug

Jian Jiang, Na Shen, Tianyuan Ci et al. · Advanced Materials · 2019 · 111 citations

Mmp9-dox-nps Exhibits, Tumor Hypoxia State, Oncology +14

Knockdown of the oncogene lncRNA NEAT1 restores the availability of <i>miR-34c</i> and improves the sensitivity to cisplatin in osteosarcoma

Yuliang Hu, Qiuyong Yang, Long Wang et al. · Bioscience Reports · 2018 · 65 citations · Full text

Combining disulfiram and poly(l-glutamic acid)-cisplatin conjugates for combating cisplatin resistance

Wantong Song, Zhaohui Tang, Na Shen et al. · Journal of Controlled Release · 2016 · 60 citations

Cisplatin Resistance, Chromatin, Medicinal Chemistry +9

Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511

Mark H. Norman, Kristin L. Andrews, Yunxin Bo et al. · Journal of Medicinal Chemistry · 2012 · 50 citations · Full text

Chemoprevention Strategy, Molecular Biology, Clinical Candidate +19