Liberty François‐Moutal

A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors

Liberty François‐Moutal, Yue Wang, Aubin Moutal et al. · Pain · 2015 · 91 citations · Full text

CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide

Aubin Moutal, Xiaofang Yang, Wennan Li et al. · Pain · 2017 · 87 citations · Full text

Pain Medicine, Pathology, Neuropathic Pain +18

Small Molecule Targeting TDP-43’s RNA Recognition Motifs Reduces Locomotor Defects in a <i>Drosophila</i> Model of Amyotrophic Lateral Sclerosis (ALS)

Liberty François‐Moutal, Razaz Felemban, David D. Scott et al. · ACS Chemical Biology · 2019 · 67 citations

(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5

Aubin Moutal, Liberty François‐Moutal, Samantha Perez‐Miller et al. · Molecular Neurobiology · 2015 · 60 citations

Molecular Physiology, Signal Transduction, Signaling Pathway +9

Inhibition of the Ubc9 E2 SUMO-conjugating enzyme–CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain

Liberty François‐Moutal, Erik T. Dustrude, Yue Wang et al. · Pain · 2018 · 59 citations · Full text

T-csm Peptide, Pain Medicine, Synaptic Transmission +24