Patrick Spinazze

Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8

Kevin M. Gardinier, Douglas L. Gernert, Warren J. Porter et al. · Journal of Medicinal Chemistry · 2016 · 58 citations · Full text

Motor Impairment, Synaptic Transmission, Neuromodulation Therapies +25

Retinoic Acid Receptor β,γ-Selective Ligands: Synthesis and Biological Activity of 6-Substituted 2-Naphthoic Acid Retinoids

Kuo‐Long Yu, Patrick Spinazze, Jacek Ostrowski et al. · Journal of Medicinal Chemistry · 1996 · 56 citations · Full text

Biological Activity, Medicinal Chemistry, γ-Selective Ligands +11

Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 1

Kumiko Takeuchi, Todd J. Kohn, Nicholas A Honigschmidt et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 48 citations · Full text

New Antidepressants, Psychoactive Drug, Psychiatry +12

Regioselective Preparation of 2,4-, 3,4-, and 2,3,4-Substituted Furan Rings. 1. [1,4] O → C and [1,4] C → O Silyl Migrations of Silyl Ethers and Esters Attached to Furan and Thiophene Rings

Edward J. Bures, Patrick Spinazze, Giovanna Beese et al. · The Journal of Organic Chemistry · 1997 · 37 citations

Asymmetric Catalysis, Chemical Engineering, Silyl Ethers +13

Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 4

Vincent P. Rocco, Patrick Spinazze, Todd J. Kohn et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 33 citations

New Antidepressants, Psychoactive Drug, Psychiatry +12