Kathryn E. Yost

Clonal replacement of tumor-specific T cells following PD-1 blockade

Kathryn E. Yost, Ansuman T. Satpathy, Daniel K. Wells et al. · Nature Medicine · 2019 · 1.5K citations

Tumor Immunology, Cancer Immunosurveillance, Medicine +6

Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion

Ansuman T. Satpathy, Jeffrey M. Granja, Kathryn E. Yost et al. · Nature Biotechnology · 2019 · 1K citations · Full text

Chromatin, Systems Biology, Lymphocyte Development +13

Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen

Santosha A. Vardhana, Madeline A. Hwee, Mirela Berisa et al. · Nature Immunology · 2020 · 489 citations · Full text

Autoimmune Disease, Mitochondrial Function, T Cells +14

Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element

Seung Woo Cho, Jin Xu, Ruping Sun et al. · Cell · 2018 · 473 citations

Chromatin, Transcriptional Regulation, Medicine +7

Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies

Kevin R. Parker, Denis Migliorini, Eric Perkey et al. · Cell · 2020 · 441 citations · Full text

Neuro-oncology, Tumor Immunology, Cancer Immunosurveillance +9