Massimiliano Fonsi

Discovery of 2-{4-[(3<i>S</i>)-Piperidin-3-yl]phenyl}-2<i>H</i>-indazole-7-carboxamide (MK-4827): A Novel Oral Poly(ADP-ribose)polymerase (PARP) Inhibitor Efficacious in BRCA-1 and -2 Mutant Tumors

Philip Jones, Sergio Altamura, Julia K. Boueres et al. · Journal of Medicinal Chemistry · 2009 · 305 citations · Full text

Characterization of the Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 ADX88178 in Rodent Models of Neuropsychiatric Disorders

Mikhail Kalinichev, Emmanuel Le Poul, Christelle Boléa et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 69 citations · Full text

Design and Synthesis of Bicyclic Pyrimidinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors

Ester Muraglia, Olaf Kinzel, Cristina Gardelli et al. · Journal of Medicinal Chemistry · 2008 · 52 citations · Full text

Discovery of a Potent Class I Selective Ketone Histone Deacetylase Inhibitor with Antitumor Activity in Vivo and Optimized Pharmacokinetic Properties

Olaf Kinzel, Laura Llauger-Bufi, Giovanna Pescatore et al. · Journal of Medicinal Chemistry · 2009 · 45 citations · Full text

Drug Target, Antitumor Activity, Pharmacotherapy +19

High-Throughput Microsomal Stability Assay for Screening New Chemical Entities in Drug Discovery

Massimiliano Fonsi, Maria Vittoria Orsale, Edith Monteagudo · SLAS DISCOVERY · 2008 · 40 citations · Full text