Einat Brill‐Almon

Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system

Yoseph Shaaltiel, Daniel Bartfeld, Sharon Hashmueli et al. · Plant Biotechnology Journal · 2007 · 429 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Pivotal trial with plant cell–expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease

Ari Zimran, Einat Brill‐Almon, Raul Chertkoff et al. · Blood · 2011 · 205 citations · Full text

Life Sciences, Plant Sciences, Glycobiology +13

A Plant-Derived Recombinant Human Glucocerebrosidase Enzyme—A Preclinical and Phase I Investigation

David Aviezer, Einat Brill‐Almon, Yoseph Shaaltiel et al. · PLoS ONE · 2009 · 185 citations · Full text

Life Sciences, Biochemistry, Pharmacokinetics +17

Pegunigalsidase alfa, a novel PEGylated enzyme replacement therapy for Fabry disease, provides sustained plasma concentrations and favorable pharmacodynamics: A 1‐year Phase 1/2 clinical trial

Raphael Schiffmann, Özlem Göker-Alpan, Myrl Holida et al. · Journal of Inherited Metabolic Disease · 2019 · 137 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +15

A Phase 3, multicenter, open-label, switchover trial to assess the safety and efficacy of taliglucerase alfa, a plant cell-expressed recombinant human glucocerebrosidase, in adult and pediatric patients with Gaucher disease previously treated with imiglucerase

Gregory M. Pastores, Мilan Petakov, Pilar Giraldo et al. · Blood Cells Molecules and Diseases · 2014 · 59 citations

Life Sciences, Biochemistry, Glycobiology +7