Concepedia

A Phase 3, multicenter, open-label, switchover trial to assess the safety and efficacy of taliglucerase alfa, a plant cell-expressed recombinant human glucocerebrosidase, in adult and pediatric patients with Gaucher disease previously treated with imiglucerase

Gregory M. Pastores, Мilan Petakov, Pilar Giraldo, Hanna Rosenbaum, Patrick Deegan, Dominick Amato, Eugen Mengel, Ee Shien Tan, Raul Chertkoff, Einat Brill‐Almon,

Blood Cells Molecules and Diseases · 2014 · 59 citations · 6 references

DOI

Concepts

References

6

Pivotal trial with plant cell–expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease

Ari Zimran, Einat Brill‐Almon, Raul Chertkoff et al. · Blood · 2011 · 205 citations · Full text

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Eight-Year Clinical Outcomes of Long-Term Enzyme Replacement Therapy for 884 Children With Gaucher Disease Type 1

Hans C. Andersson, Paige Kaplan, Katherine Kacena et al. · PEDIATRICS · 2008 · 166 citations

, , +17

First plant-made biologic approved

Jeffrey L. Fox · Nature Biotechnology · 2012 · 149 citations · Full text

, , +10

Oral maintenance clinical trial with miglustat for type I Gaucher disease: switch from or combination with intravenous enzyme replacement

Deborah Elstein, Altoon Dweck, Drorit Attias et al. · Blood · 2007 · 124 citations

, , +4

Gaucher disease: clinical profile and therapeutic developments

Timothy M. Cox · Biologics · 2010 · 111 citations · Full text

, , +17