James A. Goodrich

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

Hiroki Kaneko, Sami Dridi, Valeria Tarallo et al. · Nature · 2011 · 609 citations

Ocular Disease, Ophthalmology, Age-related Diseases +7

DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88

Valeria Tarallo, Yoshio Hirano, Bradley D. Gelfand et al. · Cell · 2012 · 586 citations · Full text

Ocular Disease, Ophthalmology, Dicer1 Loss +8

Human Alu RNA Is a Modular Transacting Repressor of mRNA Transcription during Heat Shock

Peter D. Mariner, Ryan D. Walters, Celso A. Espinoza et al. · Molecular Cell · 2008 · 461 citations · Full text

Transcriptional Regulation, Mrna Transcription, Heat Shock +11

Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB

James A. Goodrich, Timothy Hoey, Catherine J. Thut et al. · Cell · 1993 · 409 citations

Transcriptional Regulation, Systems Biology, Vp16 Activation Domain +9

Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II

Wilma A. Hofmann, Ljuba Stojiljković, Beata Fuchsová et al. · Nature Cell Biology · 2004 · 360 citations

Transcriptional Regulation, Rna Polymerase Ii, Natural Sciences +9