Yoshio Hirano

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

Hiroki Kaneko, Sami Dridi, Valeria Tarallo et al. · Nature · 2011 · 614 citations

Medicine, Molecular Biology, Molecular Genetics +11

DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88

Valeria Tarallo, Yoshio Hirano, Bradley D. Gelfand et al. · Cell · 2012 · 594 citations · Full text

Medicine, Molecular Biology, Ophthalmology +12

cGAS drives noncanonical-inflammasome activation in age-related macular degeneration

Nagaraj Kerur, Shin‐ichi Fukuda, Daipayan Banerjee et al. · Nature Medicine · 2017 · 294 citations · Full text

Medicine, Immunology, Ophthalmology +14

Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity

Benjamin J. Fowler, Bradley D. Gelfand, Young‐Hee Kim et al. · Science · 2014 · 229 citations

Veterinary Medicine, Infectious Diseases, Ophthalmology +17

TLR-Independent and P2X7-Dependent Signaling Mediate<i>Alu</i>RNA-Induced NLRP3 Inflammasome Activation in Geographic Atrophy

Nagaraj Kerur, Yoshio Hirano, Valeria Tarallo et al. · Investigative Ophthalmology & Visual Science · 2013 · 155 citations · Full text

Life Sciences, Immunology, Molecular Biology +17