Angela Hughes‐Earle

Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice

Scott B. Berger, Viera Kasparcova, Sandy Hoffman et al. · The Journal of Immunology · 2014 · 373 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Dabrafenib; Preclinical Characterization, Increased Efficacy when Combined with Trametinib, while BRAF/MEK Tool Combination Reduced Skin Lesions

Alastair J. King, Marc R. Arnone, Maureen R. Bleam et al. · PLoS ONE · 2013 · 217 citations · Full text

Medicine, Oncology, Pharmacology +16

Imaging MS in Toxicology: An Investigation of Juvenile Rat Nephrotoxicity Associated with Dabrafenib Administration

M. Reid Groseclose, Susan Laffan, Kendall S. Frazier et al. · Journal of the American Society for Mass Spectrometry · 2015 · 54 citations · Full text

Medicine, Pharmacology, Toxicology +14

Spontaneous Cardiomyopathy in Young Sprague-Dawley Rats

Franck Chanut, Carie Kimbrough, Rick Hailey et al. · Toxicologic Pathology · 2013 · 40 citations · Full text

Veterinary Medicine, Cardiology, Toxicology +16

Potential candidate genomic biomarkers of drug induced vascular injury in the rat

Deidre A. Dalmas, Marshall S. Scicchitano, David W. Mullins et al. · Toxicology and Applied Pharmacology · 2011 · 22 citations

Medicine, Molecular Genetics, Pharmacology +12