Martin Leivers

Discovery of Selective Small Molecule Type III Phosphatidylinositol 4-Kinase Alpha (PI4KIIIα) Inhibitors as Anti Hepatitis C (HCV) Agents

Anna L. Leivers, Matthew D. Tallant, J. Brad Shotwell et al. · Journal of Medicinal Chemistry · 2013 · 66 citations · Full text

Viral Replication, Viral Polymerase Structure, Hepatitis C Virus +22

Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase

Andrew Maynard, Renae M. Crosby, Byron Ellis et al. · Journal of Medicinal Chemistry · 2013 · 54 citations · Full text

Vitro Potency, Medicinal Chemistry, Viral Replication +15

Novel Spiroketal Pyrrolidine GSK2336805 Potently Inhibits Key Hepatitis C Virus Genotype 1b Mutants: From Lead to Clinical Compound

Wieslaw M. Kazmierski, Andrew Maynard, Maosheng Duan et al. · Journal of Medicinal Chemistry · 2014 · 43 citations · Full text

Rapid Clinical Progress, Interaction Model, Viral Hepatitis +12

A Randomized, Double‐Blind, Placebo‐Controlled, First‐Time‐in‐Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of GSK3389404 in Healthy Subjects

Kelong Han, Jennifer Cremer, Robert C. Elston et al. · Clinical Pharmacology in Drug Development · 2019 · 41 citations · Full text

Randomized clinical trials towards a single‐visit cure for chronic hepatitis C: Oral GSK2878175 and injectable RG‐101 in chronic hepatitis C patients and long‐acting injectable GSK2878175 in healthy participants

Yanli Deng, Fiona Campbell, Kelong Han et al. · Journal of Viral Hepatitis · 2020 · 31 citations

Hepatology, Hepatitis C, Viral Hepatitis +13