Renae M. Crosby

Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity

Rakesh Kumar, Victoria B. Knick, Sharon K. Rudolph et al. · Molecular Cancer Therapeutics · 2007 · 517 citations

Medicine, Pharmacokinetics, Pharmacology +17

Discovery of 5-[[4-[(2,3-Dimethyl-2<i>H</i>-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor

Philip A. Harris, Amogh Boloor, Mui Cheung et al. · Journal of Medicinal Chemistry · 2008 · 345 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer.

David W. Rusnak, Karen Affleck, Stuart Cockerill et al. · PubMed · 2001 · 297 citations

Medicine, Oncology, Pharmacology +15

Involvement of pp60c-src with two major signaling pathways in human breast cancer.

Deirdre K. Luttrell, A Lee, Timothy J. Lansing et al. · Proceedings of the National Academy of Sciences · 1994 · 274 citations

Life Sciences, Molecular Biology, Oncology +17

Inhibition of colony-stimulating-factor-1 signaling <i>in vivo</i> with the orally bioavailable cFMS kinase inhibitor GW2580

James G. Conway, Brad McDonald, Janet H. Parham et al. · Proceedings of the National Academy of Sciences · 2005 · 252 citations · Full text

Life Sciences, Pharmacology, Bone Metabolism +14