Matthew D. Tallant

Discovery of Selective Small Molecule Type III Phosphatidylinositol 4-Kinase Alpha (PI4KIIIα) Inhibitors as Anti Hepatitis C (HCV) Agents

Anna L. Leivers, Matthew D. Tallant, J. Brad Shotwell et al. · Journal of Medicinal Chemistry · 2013 · 66 citations · Full text

Viral Replication, Viral Polymerase Structure, Hepatitis C Virus +22

Synthesis and biological evaluations of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease

Charles Z. Ding, Yong-Kang Zhang, Xianfeng Li et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 46 citations

Biochemistry, Biological Evaluations, Medicine +8

Novel Spiroketal Pyrrolidine GSK2336805 Potently Inhibits Key Hepatitis C Virus Genotype 1b Mutants: From Lead to Clinical Compound

Wieslaw M. Kazmierski, Andrew Maynard, Maosheng Duan et al. · Journal of Medicinal Chemistry · 2014 · 43 citations · Full text

Rapid Clinical Progress, Interaction Model, Viral Hepatitis +12

Synthesis and SAR of acyclic HCV NS3 protease inhibitors with novel P4-benzoxaborole moieties

Xianfeng Li, Suoming Zhang, Yong-Kang Zhang et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 42 citations

Medicinal Chemistry, Novel P4-benzoxaborole Moieties, Natural Sciences +8

Discovery of Novel Urea-Based Hepatitis C Protease Inhibitors with High Potency against Protease-Inhibitor-Resistant Mutants

Wieslaw M. Kazmierski, Robert Hamatake, Maosheng Duan et al. · Journal of Medicinal Chemistry · 2012 · 39 citations

Immunology, Pharmacotherapy, Antiviral Drug +18