Vivian Hook

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight

Francine E. Garrett-Bakelman, Manjula Darshi, Stefan J. Green et al. · Science · 2019 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease

Evan Hermel, Juliette Gafni, Stephanie Propp et al. · Cell Death and Differentiation · 2004 · 222 citations

Life Sciences, Neurobiology, Neuroscience +13

Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter

Sukkid Yasothornsrikul, Doron C. Greenbaum, Katalin F. Medzihradszky et al. · Proceedings of the National Academy of Sciences · 2003 · 211 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14

Inhibitors of Cathepsin B Improve Memory and Reduce β-Amyloid in Transgenic Alzheimer Disease Mice Expressing the Wild-type, but Not the Swedish Mutant, β-Secretase Site of the Amyloid Precursor Protein

Vivian Hook, Mark S. Kindy, Gregory Hook · Journal of Biological Chemistry · 2008 · 204 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Inhibition of cathepsin B reduces β-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate β-secretase of Alzheimer's disease

Vivian Hook, Thomas Toneff, Matthew Bogyo et al. · Biological Chemistry · 2005 · 168 citations

Life Sciences, Biochemistry, Neuroscience +17