Concepedia

Author

Thomas Toneff

University of California San Diego

Also Known As

T. TONEFF, T. Toneff, Thomas Toneff, Thomas W. Toneff

51

Publications

2K

Citations

28

H-Index

76

Concepts

All Affiliations

University of California San DiegoUniversity of MontanaBuck Institute for Research on AgingUniversity of FreiburgTufts University
TT

About

Thomas Toneff is an author at University of California San Diego specializing in medicine, biochemistry, and natural sciences.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

17

20

1K

2

Biochemistry

11

11

626

3

Natural Sciences

10

10

713

4

Health Sciences

1

1

21

5

Social Sciences

1

1

35

Thomas Toneff

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36

Publications

1.9K

Citations

28

H-Index

YearCitations

Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter

Sukkid Yasothornsrikul, Doron C. Greenbaum, Katalin F. Medzihradszky,

Proceedings of the National Academy of Sciences

2003

210

Inhibition of cathepsin B reduces β-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate β-secretase of Alzheimer's disease

Vivian Hook, Thomas Toneff, Matthew Bogyo,

Biological Chemistry

2005

168

Tissue-Specific Proteolysis of Huntingtin (htt) in Human Brain: Evidence of Enhanced Levels of N- and C-Terminal htt Fragments in Huntington's Disease Striatum

Liane Mende‐Mueller, Thomas Toneff, Shin‐Rong Hwang,

Journal of Neuroscience

2001

158

Human iPSC Neurons Display Activity-Dependent Neurotransmitter Secretion: Aberrant Catecholamine Levels in Schizophrenia Neurons

Vivian Hook, Kristen Brennand, Yong Sung Kim,

Stem Cell Reports

2014

108

Brain Pyroglutamate Amyloid-β is Produced by Cathepsin B and is Reduced by the Cysteine Protease Inhibitor E64d, Representing a Potential Alzheimer's Disease Therapeutic

Gregory Hook, Jin Yu, Thomas Toneff,

Journal of Alzheimer s Disease

2014

83

Formation of the Catecholamine Release-inhibitory Peptide Catestatin from Chromogranin A

Carolyn V. Taylor, Laurent Taupenot, Sushil K. Mahata,

Journal of Biological Chemistry

2000

75

Major Role of Cathepsin L for Producing the Peptide Hormones ACTH, β-Endorphin, and α-MSH, Illustrated by Protease Gene Knockout and Expression

Lydiane Funkelstein, Thomas Toneff, Charles Mosier,

Journal of Biological Chemistry

2008

75

Obliteration of α‐melanocyte‐stimulating hormone derived from POMC in pituitary and brains of PC2‐deficient mice

Ruthellen Miller, Wade H. Aaron, Thomas Toneff,

Journal of Neurochemistry

2003

56

β‐Amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for β‐secretase activity in chromaffin vesicles

Vivian Hook, Thomas Toneff, Wade H. Aaron,

Journal of Neurochemistry

2002

56

Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression

Lydiane Funkelstein, Thomas Toneff, Shin‐Rong Hwang,

Journal of Neurochemistry

2008

52

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