RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain

Rashid Deane, Shi Du Yan, Ram Kumar Submamaryan, +20

Nature Medicine

NeurophysiologyMedicineAmyloid-β Peptide TransportBlood-brain BarrierBrain-immune Interaction +5

Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis

Shi Du Yan, Huaijie Zhu, Aiping Zhu, +8

Nature Medicine

Alzheimer's DiseaseStressImmunologyDegenerative PathologyProtein Misfolding +2

Neprilysin: An Enzyme Candidate to Slow the Progression of Alzheimer's Disease

Salim S. El‐Amouri, Hong Zhu, Jin Yu, +3

American Journal Of Pathology

Alzheimer's DiseaseBiochemistryMedicineDementiaDegenerative Pathology +7

Differential Modulation of Estrogen Receptors (ERs) in Ischemic Brain Injury: A Role for ERα in Estradiol-Mediated Protection against Delayed Cell Death

Dena B. Dubal, Shane W. Rau, Paul J. Shughrue, +10

Endocrinology

Cell DeathSocial SciencesOxidative StressCerebral Vascular RegulationEstradiol Protect +18

Estrogen receptor α, not β, is a critical link in estradiol-mediated protection against brain injury

Dena B. Dubal, Hong Zhu, Jin Yu, +5

Proceedings of the National Academy of Sciences

Estrogen ReceptorNeuroendocrinologyEstradiol ProtectsCerebral Vascular RegulationEstradiol Protect +14

Presenilin-1 Mutation Increases Neuronal Vulnerability to Focal Ischemia<i>In Vivo</i>and to Hypoxia and Glucose Deprivation in Cell Culture: Involvement of Perturbed Calcium Homeostasis

Mark P. Mattson, Haiyan Zhu, Jin Yu, +1

Journal of Neuroscience

Intracellular Calcium LevelsCell CultureCellular NeurobiologyCellular PhysiologySocial Sciences +21

Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors α and β

Shotaro Suzuki, Lynnette M. Gerhold, Martina Böttner, +10

The Journal of Comparative Neurology

JNK3 Signaling Pathway Activates Ceramide Synthase Leading to Mitochondrial Dysfunction

Jin Yu, Sergei A. Novgorodov, Daria A. Chudakova, +6

Journal of Biological Chemistry

Correlation Between Fecal Metabolomics and Gut Microbiota in Obesity and Polycystic Ovary Syndrome

Ling Zhou, Zhexin Ni, Jin Yu, +3

Frontiers in Endocrinology

Inflammation-Dependent Cerebral Deposition of Serum Amyloid A Protein in a Mouse Model of Amyloidosis

Jun-tao Guo, Jin Yu, David Grass, +2

Journal of Neuroscience

ImmunologyNeurochemical BiomarkersNeuroinflammationInflammationReactive Amyloid +16