Sacha Uljon

Mechanism of the cleavage specificity of Alzheimer’s disease γ-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein

Stefan F. Lichtenthaler, Rong Wang, Heike S. Grimm et al. · Proceedings of the National Academy of Sciences · 1999 · 231 citations

Human DNA Polymerase κ Encircles DNA: Implications for Mismatch Extension and Lesion Bypass

Samer Lone, Sharon A. Townson, Sacha Uljon et al. · Molecular Cell · 2007 · 226 citations · Full text

Chromatin, Genome Instability, Lesion Bypass +8

Amyloid Phenotype Characterization of Transgenic Mice Overexpressing both Mutant Amyloid Precursor Protein and Mutant Presenilin 1 Transgenes

Eileen McGowan, Sunny Sanders, Takeshi Iwatsubo et al. · Neurobiology of Disease · 1999 · 185 citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Alzheimer's Disease +9

Modulation of Aβ peptides by estrogen in mouse models

Hui Zheng, Huaxi Xu, Sacha Uljon et al. · Journal of Neurochemistry · 2001 · 175 citations

γ-Secretase, Evidence for Multiple Proteolytic Activities and Influence of Membrane Positioning of Substrate on Generation of Amyloid β Peptides of Varying Length

M. Paul Murphy, Lesley Hickman, Christopher B. Eckman et al. · Journal of Biological Chemistry · 1999 · 158 citations · Full text

Cleavage Specificity, Protein Secretion, Membrane Positioning +18