Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model

Lorenzo M. Refolo, Miguel A. Pappolla, Brian Malester, +6

Neurobiology of Disease

Alzheimer's DiseaseDementiaVascular DementiaDegenerative PathologyNeurochemical Biomarkers +10

Direct and Potent Regulation of γ-Secretase by Its Lipid Microenvironment

Pamela Osenkowski, Wenjuan Ye, Rong Wang, +2

Journal of Biological Chemistry

Proteinlipid InteractionProtein SecretionBiochemistryNatural SciencesMedicine +13

Mechanism of the cleavage specificity of Alzheimer’s disease γ-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein

Stefan F. Lichtenthaler, Rong Wang, Heike S. Grimm, +3

Proceedings of the National Academy of Sciences

Cell‐free assays for γ‐secretase activity

Chris McLendon, Tianpei A. Xin, Chewki Ziani‐Cherif, +8

The FASEB Journal

Protein SecretionAmyloid B-proteinAlzheimer's DiseaseBioanalysisDegenerative Pathology +14

Negative Role of RIG-I Serine 8 Phosphorylation in the Regulation of Interferon-β Production

Estanislao Nistal‐Villán, Michaela U. Gack, Gustavo Martínez-Delgado, +7

Journal of Biological Chemistry

Presenilin 1 Regulates Pharmacologically Distinct γ-Secretase Activities

M. Paul Murphy, Sacha Uljon, Paul E. Fraser, +8

Journal of Biological Chemistry

Resolvin D1 and D2 inhibit tumour growth and inflammation via modulating macrophage polarization

Kai Shan, Ninghan Feng, Jing Cui, +10

Journal of Cellular and Molecular Medicine

Structural Insights of the Specificity and Catalysis of a Viral Histone H3 Lysine 27 Methyltransferase

Chengmin Qian, Xueqi Wang, Karishma L. Manzur, +5

Journal of Molecular Biology

Histone ModificationsChromatinBiochemistryStructural InsightsNatural Sciences +7

Short-Term Chromium-Stress-Induced Alterations in the Maize Leaf Proteome

Rong Wang, Fei Gao, Bingqian Guo, +3

International Journal of Molecular Sciences

BotanyGeneticsMolecular BiologyPlant PathologyAbiotic Damage +19

Effects of poor sleep on the immune cell landscape as assessed by single-cell analysis

Xiuxing Liu, Binyao Chen, Zhaohao Huang, +8

Communications Biology