Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety

Lucy Brooks, Alexander Viardot, Anastasia Tsakmaki, +14

Molecular Metabolism

Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy

Polychronis Pavlidis, Anastasia Tsakmaki, Eirini Pantazi, +21

Nature Communications

Ursodeoxycholic acid enriches intestinal bile salt hydrolase-expressing Bacteroidetes in cholestatic pregnancy

Caroline Ovadia, Álvaro Perdones-Montero, Hei Man Fan, +14

Scientific Reports

Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel disease

Polychronis Pavlidis, Anastasia Tsakmaki, Agatha Treveil, +10

Cell Reports

ISX-9 manipulates endocrine progenitor fate revealing conserved intestinal lineages in mouse and human organoids

Anastasia Tsakmaki, Patricia Fonseca Pedro, Polychronis Pavlidis, +2

Molecular Metabolism

Age-related islet inflammation marks the proliferative decline of pancreatic beta-cells in zebrafish

Sharan Janjuha, Sumeet Pal Singh, Anastasia Tsakmaki, +8

eLife

Modelling pancreatic β-cell inflammation in zebrafish identifies the natural product wedelolactone for human islet protection

Luis Fernando Delgadillo-Silva, Anastasia Tsakmaki, Nadeem Akhtar, +4

Disease Models & Mechanisms

Islet neuropeptide Y receptors are functionally conserved and novel targets for the preservation of beta‐cell mass

Zara J. Franklin, Anastasia Tsakmaki, Patricia Fonseca Pedro, +5

Diabetes Obesity and Metabolism

Histologic assessment of the intestinal wall following duodenal mucosal resurfacing (DMR): a new procedure for the treatment of insulin-resistant metabolic disease

Eduardo Guimarães Hourneaux de Moura, Alberto Machado da Ponte Neto, Anastasia Tsakmaki, +3

Endoscopy International Open

Chronic peptide-based GIP receptor inhibition exhibits modest glucose metabolic changes in mice when administered either alone or combined with GLP-1 agonism

Jason A. West, Anastasia Tsakmaki, Soumitra S. Ghosh, +6

PLoS ONE