Concepedia
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Publications
5
Citations
146
H-Index
Active since
2020
Affiliations
Dalian University(Current)
Dalian University of Technology
Fangkui Yin is an author at Dalian University specializing in apoptosis, life sciences, and protein-protein interactions.
Publications per year
2020–2023
The chaperone Hsp70 is a BH3 receptor activated by the pro-apoptotic Bim to stabilize anti-apoptotic clients
Zongwei Guo, Ting Song, Ziqian Wang et al. · Journal of Biological Chemistry · 2020 · 41 citations · Full text
Life Sciences, Biochemistry, Cell Biology +17
Small-molecule inhibitor targeting the Hsp70-Bim protein–protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance
Ting Song, Yafei Guo, Zuguang Xue et al. · Leukemia · 2021 · 40 citations
Life Sciences, Cancer Biology, Molecular Biology +17
A novel Hsp70 inhibitor specifically targeting the cancer-related Hsp70-Bim protein-protein interaction
Ziqian Wang, Ting Song, Zongwei Guo et al. · European Journal of Medicinal Chemistry · 2021 · 29 citations · Full text
Life Sciences, Molecular Biology, Oncology +14
Hsp70-Bim interaction facilitates mitophagy by recruiting parkin and TOMM20 into a complex
Ting Song, Fangkui Yin, Ziqian Wang et al. · Cellular & Molecular Biology Letters · 2023 · 23 citations · Full text
Life Sciences, Biochemistry, Cell Biology +16
Exploiting the “Hot-Spots” of Hsp70<b>–</b>Bim Protein<b>–</b>Protein Interaction to Optimize the 1-Oxo-1<i>H</i>-phenalene-2,3-dicarbonitrile Analogues as Specific Hsp70<b>–</b>Bim Inhibitors
Ziqian Wang, Hong Zhang, Xin Li et al. · Journal of Medicinal Chemistry · 2023 · 13 citations
Pharmacy, Medicinal Chemistry, Pharmacology +16
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