Ziqian Wang

Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands

Ziqian Wang, Nianzhe He, Zongwei Guo et al. · Journal of Medicinal Chemistry · 2019 · 116 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +15

A self-immolative prodrug nanosystem capable of releasing a drug and a NIR reporter for in vivo imaging and therapy

Ziqian Wang, Hao Wu, Peilian Liu et al. · Biomaterials · 2017 · 69 citations

Pharmacy, Pharmaceutics, Pharmacology +16

Bcl‐2 phosphorylation confers resistance on chronic lymphocytic leukaemia cells to the BH3 mimetics ABT‐737, ABT‐263 and ABT‐199 by impeding direct binding

Ting Song, Gaobo Chai, Yubo Liu et al. · British Journal of Pharmacology · 2015 · 60 citations · Full text

Life Sciences, Cancer Biology, Pharmacology +14

A dopamine-precursor-based nanoprodrug for in-situ drug release and treatment of acute liver failure by inhibiting NLRP3 inflammasome and facilitating liver regeneration

Chenyue Zhan, Guifang Lin, Yong Huang et al. · Biomaterials · 2020 · 60 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Deactivation of Mcl‐1 by Dual‐Function Small‐Molecule Inhibitors Targeting the Bcl‐2 Homology 3 Domain and Facilitating Mcl‐1 Ubiquitination

Ting Song, Ziqian Wang, Fangling Ji et al. · Angewandte Chemie International Edition · 2016 · 47 citations

Life Sciences, Biochemistry, Molecular Biology +16