Ting Song

Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands

Ziqian Wang, Nianzhe He, Zongwei Guo et al. · Journal of Medicinal Chemistry · 2019 · 116 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +15

3-Thiomorpholin-8-oxo-8<i>H</i>-acenaphtho[1,2-<i>b</i>]pyrrole-9-carbonitrile (S1) Based Molecules as Potent, Dual Inhibitors of B-Cell Lymphoma 2 (Bcl-2) and Myeloid Cell Leukemia Sequence 1 (Mcl-1): Structure-Based Design and Structure−Activity Relationship Studies

Zhichao Zhang, Guiye Wu, Feibo Xie et al. · Journal of Medicinal Chemistry · 2011 · 87 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A novel BH3 mimetic S1 potently induces Bax/Bak‐dependent apoptosis by targeting both Bcl‐2 and Mcl‐1

Zhichao Zhang, Ting Song, Tiantai Zhang et al. · International Journal of Cancer · 2010 · 77 citations

Medicine, Oncology, Pharmacology +15

Bcl‐2 phosphorylation confers resistance on chronic lymphocytic leukaemia cells to the BH3 mimetics ABT‐737, ABT‐263 and ABT‐199 by impeding direct binding

Ting Song, Gaobo Chai, Yubo Liu et al. · British Journal of Pharmacology · 2015 · 60 citations · Full text

Life Sciences, Cancer Biology, Pharmacology +14

Remodeling tumor immunosuppressive microenvironment via a novel bioactive nanovaccines potentiates the efficacy of cancer immunotherapy

Xiaoxue Xie, Yi Feng, Hanxi Zhang et al. · Bioactive Materials · 2022 · 53 citations · Full text

Medicine, Oncology, Pharmacology +17