Isabelle Duplan

The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis

Nathalie Hennuyer, Isabelle Duplan, Charlotte Paquet et al. · Atherosclerosis · 2016 · 128 citations

Inflammation, Metabolic Syndrome, Molecular Pharmacology +12

Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice

Rebecca Deprez‐Poulain, Nathalie Hennuyer, Damien Bosc et al. · Nature Communications · 2015 · 93 citations · Full text

Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance

Manuel Lasalle, Vanessa Hoguet, Nathalie Hennuyer et al. · Journal of Medicinal Chemistry · 2017 · 59 citations · Full text

Promote Glucagon, Immunology, Gastroenterology +18

The human hepatocyte cell lines IHH and HepaRG: models to study glucose, lipid and lipoprotein metabolism

Carolina Huaman Samanez, Sandrine Caron, Olivier Briand et al. · Archives of Physiology and Biochemistry · 2012 · 57 citations

Metabolic Remodeling, Insulin Signaling, Metabolic Syndrome +19

DHA-derived oxylipins, neuroprostanes and protectins, differentially and dose-dependently modulate the inflammatory response in human macrophages: Putative mechanisms through PPAR activation

Rémy Bosviel, Laurie Joumard‐Cubizolles, Giulia Chinetti et al. · Free Radical Biology and Medicine · 2016 · 57 citations · Full text

Inflammation, Dha-derived Oxylipins, Anti-inflammatory +11