Damien Bosc

Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice

Rebecca Deprez‐Poulain, Nathalie Hennuyer, Damien Bosc et al. · Nature Communications · 2015 · 93 citations · Full text

Controlling Plasma Stability of Hydroxamic Acids: A MedChem Toolbox

Paul Hermant, Damien Bosc, Catherine Piveteau et al. · Journal of Medicinal Chemistry · 2017 · 57 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Aldehyde Dehydrogenase +15

A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B

Damien Bosc, Lubomir Vezenkov, Svetlana Bortnik et al. · Scientific Reports · 2018 · 51 citations · Full text

Development of fluorescent peptide substrates and assays for the key autophagy-initiating cysteine protease enzyme, ATG4B

Lubomir Vezenkov, Nicolette S. Honson, Nag S. Kumar et al. · Bioorganic & Medicinal Chemistry · 2015 · 40 citations

Fluorescent Peptide Substrates, Mitophagy, Protein Function +10

Discovery of a New Class of Protein Farnesyltransferase Inhibitors in the Arylthiophene Series

Sébastien Lethu, Maryon Ginisty, Damien Bosc et al. · Journal of Medicinal Chemistry · 2009 · 33 citations

Combinatorial Chemistry, Bioorganic Chemistry, Molecular Biology +18