Sébastien Lethu

Water‐Mediated Recognition of Simple Alkyl Chains by Heart‐Type Fatty‐Acid‐Binding Protein

Shigeru Matsuoka, Shigeru Sugiyama, Daisuke Matsuoka et al. · Angewandte Chemie International Edition · 2014 · 52 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Discovery of a New Class of Protein Farnesyltransferase Inhibitors in the Arylthiophene Series

Sébastien Lethu, Maryon Ginisty, Damien Bosc et al. · Journal of Medicinal Chemistry · 2009 · 33 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

New protein farnesyltransferase inhibitors in the 3-arylthiophene 2-carboxylic acid series: diversification of the aryl moiety by solid-phase synthesis

Sébastien Lethu, Damien Bosc, Elisabeth Mouray et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2012 · 28 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Synthesis and Th1-immunostimulatory activity of α-galactosylceramide analogues bearing a halogen-containing or selenium-containing acyl chain

Md. Imran Hossain, Shinya Hanashima, Takuto Nomura et al. · Bioorganic & Medicinal Chemistry · 2016 · 18 citations

Life Sciences, Chemistry, Immunology +4

Highly Efficient Preparation of Selectively Isotope Cluster-Labeled Long Chain Fatty Acids via Two Consecutive C_sp³–C_sp³ Cross-Coupling Reactions

Sébastien Lethu, Shigeru Matsuoka, Michio Murata · Organic Letters · 2014 · 16 citations

Life Sciences, Biochemistry, Chemistry +12