Manuel Lasalle

Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance

Manuel Lasalle, Vanessa Hoguet, Nathalie Hennuyer et al. · Journal of Medicinal Chemistry · 2017 · 59 citations · Full text

Promote Glucagon, Immunology, Gastroenterology +18

Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates

Mark E. Petersen, Michael G. Brant, Manuel Lasalle et al. · Molecular Cancer Therapeutics · 2024 · 17 citations · Full text

Beyond the Rule of 5: Impact of PEGylation with Various Polymer Sizes on Pharmacokinetic Properties, Structure–Properties Relationships of mPEGylated Small Agonists of TGR5 Receptor

Vanessa Hoguet, Manuel Lasalle, Mathieu Maingot et al. · Journal of Medicinal Chemistry · 2021 · 14 citations

Generation and structure-activity relationships of novel imidazo-thienopyridine based TLR7 agonists: application as payloads for immunostimulatory antibody drug-conjugates

Michael G. Brant, Graham A. E. Garnett, Joy Guedia et al. · Bioorganic & Medicinal Chemistry Letters · 2023 · 11 citations · Full text