Mike Costa

TSPAN12 Regulates Retinal Vascular Development by Promoting Norrin- but Not Wnt-Induced FZD4/β-Catenin Signaling

Harald J. Junge, Stacey C. Yang, Jeremy B. Burton et al. · Cell · 2009 · 377 citations · Full text

Ocular Disease, Developmental Biology, Signal Transduction +11

A Novel Tankyrase Small-Molecule Inhibitor Suppresses <i>APC</i> Mutation–Driven Colorectal Tumor Growth

Ted Lau, Emily Chan, Marinella Callow et al. · Cancer Research · 2013 · 317 citations

Reconstitution of a Frizzled8·Wnt3a·LRP6 Signaling Complex Reveals Multiple Wnt and Dkk1 Binding Sites on LRP6

Eric Bourhis, Christine Tam, Yvonne Franke et al. · Journal of Biological Chemistry · 2010 · 226 citations · Full text

Ubiquitin Ligase RNF146 Regulates Tankyrase and Axin to Promote Wnt Signaling

Marinella Callow, Hoanh Tran, Lilian Phu et al. · PLoS ONE · 2011 · 222 citations · Full text

Molecular Regulation, Axin Scaffolding, Rnf146 Protein Levels +20

Opposing Activities of Notch and Wnt Signaling Regulate Intestinal Stem Cells and Gut Homeostasis

Hua Tian, Brian Biehs, Cecilia Chiu et al. · Cell Reports · 2015 · 207 citations · Full text