Alain Bonnefoy

Synthesis and Antibacterial Activity of Ketolides (6-<i>O</i>-Methyl-3-oxoerythromycin Derivatives):  A New Class of Antibacterials Highly Potent Against Macrolide-Resistant and -Susceptible Respiratory Pathogens

Constantin Agouridas, Alexis Denis, Jean-Michel Auger et al. · Journal of Medicinal Chemistry · 1998 · 199 citations

Bioorganic Chemistry, Antibacterial Activity, Macrolactone Backbone +21

Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens

Alexis Denis, Constantin Agouridas, Jean-Michel Auger et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 195 citations

Antibiotics, Hmr 3647, Antibacterial Activity +10

Ketolides lack inducibility properties of MLS(B) resistance phenotype

Alain Bonnefoy · Journal of Antimicrobial Chemotherapy · 1997 · 182 citations

Induction Kinetics, Inducing Activity, Drug Resistance Analysis +15

In vitro activity of AVE1330A, an innovative broad-spectrum non- -lactam  -lactamase inhibitor

Alain Bonnefoy · Journal of Antimicrobial Chemotherapy · 2004 · 172 citations

Synthesis and in vitro evaluation of novel highly potent coumarin inhibitors of gyrase B

Patrick Laurin, Didier Ferroud, Michel Klich et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 154 citations

Inhibitory Activity, Medicinal Chemistry, Pharmaceutical Science +11