Patrick Laurin

Synthesis and Antibacterial Activity of Ketolides (6-<i>O</i>-Methyl-3-oxoerythromycin Derivatives):  A New Class of Antibacterials Highly Potent Against Macrolide-Resistant and -Susceptible Respiratory Pathogens

Constantin Agouridas, Alexis Denis, Jean-Michel Auger et al. · Journal of Medicinal Chemistry · 1998 · 199 citations

Bioorganic Chemistry, Antibacterial Activity, Macrolactone Backbone +21

Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens

Alexis Denis, Constantin Agouridas, Jean-Michel Auger et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 195 citations

Antibiotics, Hmr 3647, Antibacterial Activity +10

Synthesis and in vitro evaluation of novel highly potent coumarin inhibitors of gyrase B

Patrick Laurin, Didier Ferroud, Michel Klich et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 154 citations

Inhibitory Activity, Medicinal Chemistry, Pharmaceutical Science +11

Improved antibacterial activities of coumarin antibiotics bearing 5′,5′-dialkylnoviose: biological activity of RU79115

Branislav Musicki, Anne‐Marie Periers, Patrick Laurin et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 123 citations

Biological Activity, Coumarin Antibiotics, Biochemistry +8

Structure-activity relationship in two series of aminoalkyl substituted coumarin inhibitors of gyrase B

Patrick Laurin, Didier Ferroud, Laurent Schio et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 55 citations

Medicinal Chemistry, Biochemistry, Medicine +11