Jae‐Hoon Chang

Inflammatory T Cell Responses Rely on Amino Acid Transporter ASCT2 Facilitation of Glutamine Uptake and mTORC1 Kinase Activation

Mako Nakaya, Yichuan Xiao, Xiaofei Zhou et al. · Immunity · 2014 · 824 citations · Full text

Inflammation, Signal Transduction, Autoimmune Disease +12

OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3

Hongbo Hu, George C. Brittain, Jae‐Hoon Chang et al. · Nature · 2013 · 222 citations

Inflammation, Signal Transduction, Non-canonical Nf-κb Activation +6

The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity

Mikyoung Chang, Wei Jin, Jae‐Hoon Chang et al. · Nature Immunology · 2011 · 200 citations · Full text

T Cell Activation, Ubiquitin Ligase Peli1, Autoimmune Disease +12

Regulatory T cell-targeted hybrid nanoparticles combined with immuno-checkpoint blockage for cancer immunotherapy

Wenquan Ou, Raj Kumar Thapa, Liyuan Jiang et al. · Journal of Controlled Release · 2018 · 191 citations

Nanomedicine, Cancer Immunosurveillance, Medicine +10

Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

Yichuan Xiao, Jin Jin, Mikyoung Chang et al. · Nature Medicine · 2013 · 182 citations · Full text

Inflammation, Medicine, Immunology +5