Concepedia

George C. Brittain

GC

10

Publications

1.1K

Citations

10

H-Index

2011

Active since

Affiliations

The University of Texas MD Anderson Cancer Center(Current)

University of Houston

Beckman Coulter Foundation

Institute of Infection and Immunity

University of Ottawa

George C. Brittain is an author at The University of Texas MD Anderson Cancer Center specializing in medicine, immunology, and cell biology.

Top concepts

MedicineImmunologyCell BiologyCell SignalingImmune RegulationVirologyInflammationSignal TransductionBiophysicsMicroscopy

Publications per year

2011–2019

10

Publications

10

OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3

Hongbo Hu, George C. Brittain, Jae‐Hoon Chang et al. · Nature · 2013 · 222 citations

Inflammation, Signal Transduction, Non-canonical Nf-κb Activation +6

The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity

Mikyoung Chang, Wei Jin, Jae‐Hoon Chang et al. · Nature Immunology · 2011 · 200 citations · Full text

T Cell Activation, Ubiquitin Ligase Peli1, Autoimmune Disease +12

Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

Yichuan Xiao, Jin Jin, Mikyoung Chang et al. · Nature Medicine · 2013 · 182 citations · Full text

Inflammation, Medicine, Immunology +5

Noncanonical NF-κB Pathway Controls the Production of Type I Interferons in Antiviral Innate Immunity

Jin Jin, Hongbo Hu, Haiyan S. Li et al. · Immunity · 2014 · 134 citations · Full text

Antiviral Innate Immunity, Pathogenesis, Viral Pathogenesis +14

The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling

Jin Jin, Yichuan Xiao, Jae‐Hoon Chang et al. · Nature Immunology · 2012 · 128 citations · Full text

Transcriptional Regulation, Iga Class Switching, Signal Transduction +13

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