Regulatory T cell-targeted hybrid nanoparticles combined with immuno-checkpoint blockage for cancer immunotherapy

Wenquan Ou, Raj Kumar Thapa, Liyuan Jiang, +8

Journal of Controlled Release

NanomedicineCancer ImmunosurveillanceMedicineImmunologyTherapeutic Vaccine +8

Transferrin-Conjugated Polymeric Nanoparticle for Receptor-Mediated Delivery of Doxorubicin in Doxorubicin-Resistant Breast Cancer Cells

Zar Chi Soe, Jun Bum Kwon, Raj Kumar Thapa, +8

Pharmaceutics

Anti-CTLA-4 antibody-functionalized dendritic cell-derived exosomes targeting tumor-draining lymph nodes for effective induction of antitumor T-cell responses

Cao Dai Phung, Tung Thanh Pham, Hanh Thuy Nguyen, +7

Acta Biomaterialia

Effective InductionTumor ImmunologyCancer ImmunosurveillanceMedicineImmunology +8

Folate-targeted nanostructured chitosan/chondroitin sulfate complex carriers for enhanced delivery of bortezomib to colorectal cancer cells

Zar Chi Soe, Bijay Kumar Poudel, Hanh Thuy Nguyen, +10

Asian Journal of Pharmaceutical Sciences

Targeting and clearance of senescent foamy macrophages and senescent endothelial cells by antibody-functionalized mesoporous silica nanoparticles for alleviating aorta atherosclerosis

Le Minh Pham, Eok-Cheon Kim, Wenquan Ou, +11

Biomaterials

NanoparticlesNanomedicineEngineeringNanobiotechnologyImmunology +8

Combination of NIR therapy and regulatory T cell modulation using layer-by-layer hybrid nanoparticles for effective cancer photoimmunotherapy

Wenquan Ou, Liyuan Jiang, Raj Kumar Thapa, +7

Theranostics

Folate receptor-mediated celastrol and irinotecan combination delivery using liposomes for effective chemotherapy

Zar Chi Soe, Raj Kumar Thapa, Wenquan Ou, +8

Colloids and Surfaces B Biointerfaces

Effective ChemotherapyNanomedicineCell-based Drug DeliveryFolate Receptor-mediated CelastrolTumor Targeting +4

Plug-and-Play Nanorization of Coarse Black Phosphorus for Targeted Chemo-photoimmunotherapy of Colorectal Cancer

Wenquan Ou, Jeong Hoon Byeon, Raj Kumar Thapa, +3

ACS Nano

Cold-Responsive Nanoparticle Enables Intracellular Delivery and Rapid Release of Trehalose for Organic-Solvent-Free Cryopreservation

Yuntian Zhang, Hai Wang, Samantha Stewart, +4

Nano Letters

In-situ cryo-immune engineering of tumor microenvironment with cold-responsive nanotechnology for cancer immunotherapy

Wenquan Ou, Samantha Stewart, Alisa White, +10

Nature Communications