Roderick E. Hubbard

Molecular basis of agonism and antagonism in the oestrogen receptor

A.M. Brzozowski, A.C.W. Pike, Zbigniew Dauter et al. · Nature · 1997 · 3.3K citations

Life Sciences, Endocrinology, Pharmacology +14

Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport

Stephen C. Hyde, Paul Emsley, Michael J. Hartshorn et al. · Nature · 1990 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +13

rDock: A Fast, Versatile and Open Source Program for Docking Ligands to Proteins and Nucleic Acids

Sergio Ruiz‐Carmona, Daniel Álvarez-García, Nicolas Foloppe et al. · PLoS Computational Biology · 2014 · 654 citations · Full text

Pharmacy, Chemical Biology, Medicinal Chemistry +17

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 478 citations · Full text

Medicine, Oncology, Pharmacology +8

4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

Paul A. Brough, Wynne Aherne, Xavier Barril et al. · Journal of Medicinal Chemistry · 2007 · 445 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11