Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport

Stephen C. Hyde, Paul Emsley, Michael J. Hartshorn, +7

Nature

Protein SecretionProtein FunctionBiochemistryProtein AssemblyNatural Sciences +6

Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein

Miguel A. Valverde, Francisco V. Sepúlveda, Deborah R. Gill, +2

Nature

Molecular PharmacologyMolecular PhysiologyHealth SciencesG Protein-coupled ReceptorMedicine +10

Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy

Stephen C. Hyde, Deborah R. Gill, Christopher F. Higgins, +6

Nature

Knockout MouseFibrosisMolecular PhysiologyIn Vivo Gene TherapyImmunology +8

Immunocytochemical localization of the cystic fibrosis gene product CFTR.

Isabelle T. Crawford, Peter C. Maloney, Pamela L. Zeitlin, +6

Proceedings of the National Academy of Sciences

InflammationCytokineFibrosisMolecular PhysiologyProtein Expression +11

Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial

Eric W.F.W. Alton, David K Armstrong, Deborah Ashby, +77

The Lancet Respiratory Medicine

Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein

Deborah R. Gill, Stephen C. Hyde, Christopher F. Higgins, +3

Cell

BiochemistryMedicineMembrane TransportChloride Channel FunctionsDrug Transport +3

Copper‐Catalyzed Insertion into Heteroatom–Hydrogen Bonds with Trifluorodiazoalkanes

Stephen C. Hyde, Janis Veliks, Benoît Liégault, +3

Angewandte Chemie International Edition

The multidrug resistance and cystic fibrosis genes have complementary patterns of epithelial expression.

A. E. O. Trezise, Pascale R. Romano, Deborah R. Gill, +4

The EMBO Journal

Cystic Fibrosis GenesFibrosisAntimicrobial Resistance GeneInflammatory Lung DiseasePathology +11

Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus

Damien J. Downes, Amy Cross, Hua Peng, +16

Nature Genetics

Tamoxifen blocks chloride channels. A possible mechanism for cataract formation.

J J Zhang, T.J.C. Jacob, Miguel A. Valverde, +7

Journal of Clinical Investigation

Molecular PharmacologyOcular DiseaseOphthalmologyMedicinePhysiology +10