Daniel Spinks

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Susan Wyllie, Stephen Brand, Michael G. Thomas et al. · Proceedings of the National Academy of Sciences · 2019 · 165 citations · Full text

Discovery of a Novel Class of Orally Active Trypanocidal <i>N</i>-Myristoyltransferase Inhibitors

Stephen Brand, Laura A. T. Cleghorn, Stuart P. McElroy et al. · Journal of Medicinal Chemistry · 2011 · 115 citations · Full text

One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening

Chidochangu P. Mpamhanga, Daniel Spinks, L.B. Tulloch et al. · Journal of Medicinal Chemistry · 2009 · 105 citations · Full text

Chemical Validation of Trypanothione Synthetase

Leah S. Torrie, Susan Wyllie, Daniel Spinks et al. · Journal of Biological Chemistry · 2009 · 79 citations · Full text

Dissecting the essentiality of the bifunctional trypanothione synthetase‐amidase in <i>Trypanosoma brucei</i> using chemical and genetic methods

Susan Wyllie, Sandra L. Oza, Stephen Patterson et al. · Molecular Microbiology · 2009 · 76 citations · Full text

Genetic Methods, Antiparasitic Agent, Immunology +19