Laura A. T. Cleghorn

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

Julie A. Frearson, Stephen Brand, Stuart P. McElroy et al. · Nature · 2010 · 311 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Respiratory Flexibility in Response to Inhibition of Cytochrome <i>c</i> Oxidase in Mycobacterium tuberculosis

Kriti Arora, Bernardo Ochoa‐Montaño, Patricia Tsang et al. · Antimicrobial Agents and Chemotherapy · 2014 · 130 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Discovery of a Novel Class of Orally Active Trypanocidal <i>N</i>-Myristoyltransferase Inhibitors

Stephen Brand, Laura A. T. Cleghorn, Stuart P. McElroy et al. · Journal of Medicinal Chemistry · 2011 · 116 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacokinetics +17

Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against<i>Mycobacterium tuberculosis</i>

Yumi Park, A. Pacitto, Tracy Bayliss et al. · ACS Infectious Diseases · 2016 · 91 citations

Life Sciences, Molecular Biology, Pharmacology +13

Investigation of Trypanothione Reductase as a Drug Target in <i>Trypanosoma brucei</i>

Daniel Spinks, Emma Shanks, Laura A. T. Cleghorn et al. · ChemMedChem · 2009 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16