Emma Shanks

Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress

Zachary T. Schug, Barrie Peck, Dylan T. Jones et al. · Cancer Cell · 2015 · 796 citations · Full text

Predicting Cancer-Specific Vulnerability via Data-Driven Detection of Synthetic Lethality

Livnat Jerby‐Arnon, Nadja Pfetzer, Yedael Y. Waldman et al. · Cell · 2014 · 296 citations · Full text

Engineering, Predictive Toxicology, Medicine +7

Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments

Barrie Peck, Zachary T. Schug, Beatrice Dankworth et al. · Cancer & Metabolism · 2016 · 261 citations · Full text

Targeting the <scp>LOX</scp> / <scp>hypoxia</scp> axis reverses many of the features that make pancreatic cancer deadly: inhibition of <scp>LOX</scp> abrogates metastasis and enhances drug efficacy

Bryan W. Miller, Jennifer P. Morton, Mark Pinese et al. · EMBO Molecular Medicine · 2015 · 259 citations · Full text

Tumor Biology, Oncology, Pancreatic Cancer +14

Harnessing synthetic lethality to predict the response to cancer treatment

Joo Sang Lee, Avinash Das, Livnat Jerby‐Arnon et al. · Nature Communications · 2018 · 139 citations · Full text