Julie A. Frearson

Lessons Learnt from Assembling Screening Libraries for Drug Discovery for Neglected Diseases

Ruth Brenk, Alessandro Schipani, Daniel James et al. · ChemMedChem · 2007 · 694 citations · Full text

Pharmacy, Medicinal Chemistry, Drug Design +16

A novel multiple-stage antimalarial agent that inhibits protein synthesis

Beatriz Baragaña, Irene Hallyburton, Neil R. Norcross et al. · Nature · 2015 · 465 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

Julie A. Frearson, Stephen Brand, Stuart P. McElroy et al. · Nature · 2010 · 311 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Comparison of a High-Throughput High-Content Intracellular Leishmania donovani Assay with an Axenic Amastigote Assay

Manu De Rycker, Irene Hallyburton, John Thomas et al. · Antimicrobial Agents and Chemotherapy · 2013 · 149 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacology +14

Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein Crystallography

Stephen Patterson, M.S. Alphey, Deuan C. Jones et al. · Journal of Medicinal Chemistry · 2011 · 131 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16